A novel missense variant in the nuclear localization signal of POU4F3 causes...
AbstractAutosomal dominant non-syndromic hearing loss (ADNSHL) is genetically heterogeneous with more than 35 genes identified to date. Using a massively parallel sequencing panel targeting 159...
View ArticleTesticular sperm is superior to ejaculated sperm for ICSI in...
AbstractIntracytoplasmic sperm injection (ICSI) is well established and provides patients with severely impaired sperm quality with an opportunity to father a child. However, previous studies do not...
View ArticleCorrelation between early clinical exposure environment, attitudes toward...
AbstractBackgroundEarly clinical exposure (ECE) is viewed as a way to provide contexts of basic science and highlight its relevance to medical practice. However, very few studies have specifically...
View ArticleGenEpi: gene-based epistasis discovery using machine learning
AbstractBackgroundGenome-wide association studies (GWAS) provide a powerful means to identify associations between genetic variants and phenotypes. However, GWAS techniques for detecting epistasis, the...
View ArticleRepression of the transcriptional activity of ERRα with sequence-specific...
AbstractThe orphan nuclear receptors estrogen-related receptors (ERRs) bind to the estrogen-related receptor response element (ERRE) to regulate transcriptional programs in cellular metabolism and...
View ArticleProminent facial feature and hybrid learning method-based advanced face...
AbstractFace detection is important for computer vision. Until now, the Viola and Jones algorithm is still the most popular face detector embedded in digital cameras. Although it has good performance...
View ArticleHow technology-enhanced experiential e-learning can facilitate the...
AbstractBackgroundThe COVID-19 pandemic brought a new challenge to medical education—health-care students had fewer opportunities to interact with and treat real patients in clinical settings....
View ArticleVariations in intraocular pressure and visual parameters before and after...
AbstractWe examined the effects of using mobile devices with immersive virtual reality for a short period on the physiological parameters of both eyes. The average age of the 50 participants (23 men...
View ArticleMolecular characterization of hepatitis B virus (HBV) isolated from a...
AbstractBackgroundTenofovir disoproxil fumarate (TDF) is effectively used as the first-line antiviral for chronic hepatitis B virus (HBV) infection in adults and children older than 12 years. To date,...
View ArticleMolecular characterization and genotyping of hepatitis C virus from Sudanese...
AbstractBackgroundHepatitis C virus (HCV) is a global public health problem, with ~ 11 million people in Africa infected. There is incomplete information on HCV in Sudan, particularly in haemodialysis...
View ArticlePreventing shivering with adjuvant low dose intrathecal meperidine: A...
AbstractThe aim of this systematic review and meta-analysis is to evaluate the pros and cons of adjuvant low dose intrathecal meperidine for spinal anaesthesia. We searched electronic databases for...
View ArticleEffect of de novo transcriptome assembly on transcript quantification
AbstractCorrect quantification of transcript expression is essential to understand the functional elements in different physiological conditions. For the organisms without the reference transcriptome,...
View ArticleAuthor Correction: Effect of de novo transcriptome assembly on transcript...
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
View ArticleA systematic review with network meta-analysis on mono strategy of...
AbstractThe aim of this study was to reveal the effects of anaesthesia strategies on maternal mean arterial pressure (MAP), heart rate, vasopressor consumption, adverse events, and neonatal...
View ArticleRecommendation for management of patients with their first episode of primary...
AbstractInternational guidelines do not recommend surgery for the first episode of primary spontaneous pneumothorax (PSP), except in cases of persistent air leak, hemopneumothorax, bilateral...
View ArticleA theoretical framework for general design of two-materials composed...
AbstractNear 100% of diffractive efficiency for diffractive optical elements (DOEs) is one of the most required optical performances in broadband imaging applications. Of all flat DOEs, none seems to...
View ArticleConnecting MHC-I-binding motifs with HLA alleles via deep learning
AbstractThe selection of peptides presented by MHC molecules is crucial for antigen discovery. Previously, several predictors have shown impressive performance on binding affinity. However, the...
View ArticleInhibition of iRhom1 by CD44-targeting nanocarrier for improved cancer...
AbstractThe multifaceted chemo-immune resistance is the principal barrier to achieving cure in cancer patients. Identifying a target that is critically involved in chemo-immune-resistance represents an...
View ArticleIndigenizing and co-producing the ACGME anesthesiology milestone in Taiwan: a...
AbstractBackgroundTo implement the ACGME Anesthesiology Milestone Project in a non-North American context, a process of indigenization is essential. In this study, we aim to explore the differences in...
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